/* MetaTarget shared theme — single source of truth for BOTH Explore and Analyze.
   Restyling the whole site = edit THIS file (then rerun analyze/build_standalone.py to refresh the
   offline single-file build, which inlines this CSS). Markup is plain semantic HTML + a few utility
   classes, so this modern visual pass (palette/typography/spacing/shadows/motion/responsive) is
   CSS-only — no JS or structural changes. Data-viz colors (--blue/--up/--down/--ok) are unchanged so
   the SVG glyphs/bars keep their meaning; only the UI chrome is modernized. v2 (2026-06-22). */

:root {
  /* surfaces & ink (warm-cool slate scale, v4 refined) */
  --bg:#eef3f3; --bg2:#e4ecec; --card:#ffffff; --ink:#0d1a1c; --ink2:#2f4247; --mut:#5f7278;
  --line:#dce6e6; --line2:#eaf1f1;
  /* brand accent (v4 — deep teal-emerald + cyan pop; UI chrome only) */
  --accent:#0d9488; --accent2:#22d3ee; --accent-ink:#0f766e; --accent-soft:#e3f4f1;
  /* elite highlight (amber-gold) — Tier-1 drivers, causally-supported, spatially-active */
  --gold:#f59e0b; --gold-ink:#b45309; --gold-soft:#fdf2dd;
  /* data-viz semantics (UNCHANGED — SVG glyphs/bars keep their meaning) */
  --blue:#2c7fb8; --up:#c0392b; --down:#2c6fbb; --ok:#1a9850;
  /* shape & depth (softer, layered) */
  --r:11px; --r-lg:16px; --r-sm:8px;
  --sh-sm:0 1px 2px rgba(9,26,28,.05), 0 1px 1px rgba(9,26,28,.04);
  --sh:0 6px 18px rgba(9,26,28,.07), 0 2px 5px rgba(9,26,28,.05);
  --sh-lg:0 18px 42px rgba(9,26,28,.14), 0 4px 12px rgba(9,26,28,.07);
  --tr:.2s cubic-bezier(.4,0,.2,1);
  --tr-slow:.5s cubic-bezier(.22,1,.36,1);
}
* { box-sizing:border-box; }
html { -webkit-text-size-adjust:100%; }
body {
  margin:0; color:var(--ink);
  font:14.5px/1.6 "Inter",-apple-system,"Segoe UI",Roboto,Helvetica,Arial,sans-serif;
  -webkit-font-smoothing:antialiased; text-rendering:optimizeLegibility;
  background:
    radial-gradient(1100px 520px at 100% -10%, #d9f0ec 0%, transparent 60%),
    radial-gradient(920px 520px at -10% 2%, #dcf0f6 0%, transparent 55%),
    radial-gradient(760px 620px at 60% 108%, #e7f4e9 0%, transparent 60%),
    var(--bg);
  background-attachment:fixed;
}
/* slow-drifting aurora wash behind everything (very subtle; disabled for reduced-motion) */
body::before {
  content:""; position:fixed; inset:-20% -10% -10% -10%; z-index:-1; pointer-events:none; opacity:.55;
  background:
    radial-gradient(560px 420px at 20% 25%, rgba(13,148,136,.10), transparent 62%),
    radial-gradient(520px 420px at 82% 20%, rgba(34,211,238,.10), transparent 60%),
    radial-gradient(560px 480px at 70% 90%, rgba(16,185,129,.08), transparent 62%);
  animation:auroraDrift 26s ease-in-out infinite alternate;
}
@keyframes auroraDrift {
  0%   { transform:translate3d(0,0,0) scale(1); }
  50%  { transform:translate3d(-2.2%,1.6%,0) scale(1.05); }
  100% { transform:translate3d(2%,-1.4%,0) scale(1.03); }
}

/* ---------- header ---------- */
header {
  background:linear-gradient(115deg,#062522 0%,#0d4d47 46%,#0d9488 100%);
  color:#fff; padding:22px 28px 20px; position:relative;
  box-shadow:var(--sh); border-bottom:1px solid rgba(255,255,255,.08);
}
header::after { /* thin accent strip */
  content:""; position:absolute; left:0; right:0; bottom:0; height:2px;
  background:linear-gradient(90deg,var(--accent),var(--accent2));
}
header h1 { margin:0; font-size:22px; font-weight:700; letter-spacing:-.01em; }
header p { margin:5px 0 0; font-size:13.5px; color:rgba(255,255,255,.82); }
header .tag {
  font-size:12px; margin-top:10px; display:flex; flex-wrap:wrap; align-items:center;
  gap:6px 4px; color:rgba(255,255,255,.6);
}
/* readable, high-contrast nav links (was invisible default-blue on dark bg) */
header a, a.back {
  color:#dbe6ff; text-decoration:none; font-weight:500;
  padding:2px 8px; border-radius:999px; background:rgba(255,255,255,.08);
  border:1px solid rgba(255,255,255,.14); transition:var(--tr); white-space:nowrap;
}
header a:hover, a.back:hover { color:#fff; background:rgba(255,255,255,.18); border-color:rgba(255,255,255,.3); }

/* ---------- layout ---------- */
.wrap { max-width:1240px; margin:0 auto; padding:26px 28px 40px; }
.panel { background:var(--card); border:1px solid var(--line); border-radius:var(--r-lg);
  padding:18px 20px; margin-bottom:18px; box-shadow:var(--sh-sm); }
.panel h2 { margin:0 0 12px; font-size:15px; font-weight:650; letter-spacing:-.01em; }

/* ---------- controls / forms ---------- */
.controls { display:flex; gap:12px; align-items:center; flex-wrap:wrap; margin-bottom:14px; }
.controls label { font-size:12.5px; color:var(--mut); display:flex; gap:6px; align-items:center; }
select,input { font:14px inherit; color:var(--ink); padding:8px 11px; border:1px solid var(--line);
  border-radius:var(--r-sm); background:#fff; transition:var(--tr); }
select:hover,input:hover { border-color:#cbd5e1; }
select:focus,input:focus { outline:none; border-color:var(--accent);
  box-shadow:0 0 0 3px var(--accent-soft); }
input[type=number] { width:92px; }
input.search { flex:1; min-width:220px; }
button { font:14px inherit; font-weight:550; padding:8px 17px; border:0; border-radius:var(--r-sm);
  background:linear-gradient(180deg,var(--accent),var(--accent-ink)); color:#fff; cursor:pointer;
  box-shadow:var(--sh-sm); transition:var(--tr); }
button:hover { filter:brightness(1.07); box-shadow:var(--sh); transform:translateY(-1px); }
button.ghost { background:#fff; color:var(--ink); border:1px solid var(--line); }
button.ghost:hover { background:var(--bg2); }
button:disabled { opacity:.5; cursor:default; transform:none; box-shadow:none; }
.map { display:grid; grid-template-columns:repeat(auto-fill,minmax(220px,1fr)); gap:10px; margin-top:12px; }
.map .req b { color:var(--up); }
code { background:var(--bg2); padding:1.5px 6px; border-radius:5px; font-size:12.5px;
  font-family:"SFMono-Regular",ui-monospace,Menlo,Consolas,monospace; color:var(--accent-ink); }
.hint { color:var(--mut); font-size:12.5px; }
.meta { color:var(--mut); font-size:12.5px; margin:6px 0 10px; }
#status { font-size:13px; color:var(--mut); margin-left:8px; }

/* ---------- stat cards ---------- */
.cards { display:flex; gap:14px; flex-wrap:wrap; margin-bottom:20px; }
.card { background:var(--card); border:1px solid var(--line); border-radius:var(--r-lg);
  padding:16px 20px; min-width:158px; flex:1; box-shadow:var(--sh-sm); transition:var(--tr);
  position:relative; overflow:hidden; }
.card::before { content:""; position:absolute; left:0; top:0; bottom:0; width:3px;
  background:linear-gradient(180deg,var(--accent),var(--accent2)); opacity:.9; }
.card:hover { transform:translateY(-2px); box-shadow:var(--sh); border-color:#d3dce8; }
.card .n { font-size:27px; font-weight:750; letter-spacing:-.02em;
  background:linear-gradient(120deg,var(--accent-ink),var(--accent2));
  -webkit-background-clip:text; background-clip:text; -webkit-text-fill-color:transparent; }
.card .l { color:var(--mut); font-size:12px; margin-top:2px; }

/* ---------- tables ---------- */
.tablewrap { background:var(--card); border:1px solid var(--line); border-radius:var(--r-lg);
  overflow:auto; max-height:72vh; box-shadow:var(--sh-sm); }
table { border-collapse:separate; border-spacing:0; width:100%; font-size:13px; }
th,td { padding:8px 12px; border-bottom:1px solid var(--line2); text-align:left; white-space:nowrap; }
th { position:sticky; top:0; z-index:1; cursor:pointer; user-select:none;
  background:rgba(244,247,251,.92); backdrop-filter:blur(6px); color:var(--ink2);
  font-weight:600; font-size:11.5px; letter-spacing:.02em; text-transform:uppercase;
  border-bottom:1px solid var(--line); }
th:hover { background:#e8eef6; color:var(--accent-ink); }
tbody tr:nth-child(even) td { background:#fbfcfe; }
tbody tr:hover td { background:var(--accent-soft); }
td.num { text-align:right; font-variant-numeric:tabular-nums; }
.up { color:var(--up); font-weight:600; }
.down { color:var(--down); font-weight:600; }
.pill { font-size:11px; padding:2px 9px; border-radius:999px; background:#e6f6ec; color:var(--ok);
  font-weight:600; border:1px solid #c7ecd4; }

/* ---------- footer ---------- */
footer { color:var(--mut); font-size:12px; padding:22px 24px 30px; text-align:center;
  border-top:1px solid var(--line); margin-top:10px; }
footer code { font-size:11.5px; }

/* ---------- responsive ---------- */
@media (max-width:760px){
  .wrap { padding:18px 16px 32px; }
  header { padding:18px 16px 16px; }
  .cards .card { min-width:120px; }
}

/* ============================================================================
   APP-SHELL (sidebar + topbar) — injected by app.js on Explore pages. v3.
   ============================================================================ */
body.has-shell { margin:0; }
.shell { display:flex; align-items:flex-start; min-height:100vh; }

/* sidebar */
.sidebar { flex:0 0 232px; width:232px; align-self:stretch; position:sticky; top:0; height:100vh;
  display:flex; flex-direction:column; gap:4px; padding:16px 14px;
  background:linear-gradient(180deg,#062522 0%,#0c3b37 100%); color:#cfe3df;
  border-right:1px solid rgba(255,255,255,.06); }
.sidebar .brand { display:flex; align-items:center; gap:10px; text-decoration:none; color:#fff;
  padding:6px 8px 14px; }
.sidebar .brand-mark { width:34px; height:34px; flex:0 0 34px; display:flex; align-items:center;
  justify-content:center; border-radius:10px; font-size:17px;
  background:linear-gradient(140deg,var(--accent),var(--accent2)); box-shadow:var(--sh); }
.sidebar .brand b { font-size:15px; font-weight:700; letter-spacing:-.01em; display:block; }
.sidebar .brand small { font-size:10.5px; color:#8fa1c2; letter-spacing:.02em; }
.sidebar .nav { display:flex; flex-direction:column; gap:2px; }
.sidebar .nv-grp { font-size:10px; font-weight:700; letter-spacing:.1em; text-transform:uppercase;
  color:#6f82a6; padding:14px 10px 5px; }
.sidebar .nv { display:flex; align-items:center; gap:11px; text-decoration:none; color:#c2cee4;
  font-size:13.5px; font-weight:500; padding:9px 11px; border-radius:9px; transition:var(--tr); }
.sidebar .nv .nv-ic { width:20px; text-align:center; font-size:14px; opacity:.95; }
.sidebar .nv:hover { background:rgba(255,255,255,.07); color:#fff; }
.sidebar .nv.active { background:linear-gradient(90deg,rgba(13,148,136,.38),rgba(34,211,238,.16));
  color:#fff; box-shadow:inset 0 0 0 1px rgba(255,255,255,.12); }
.sidebar .sb-foot { margin-top:auto; padding-top:12px; }
.theme-btn { width:100%; display:flex; align-items:center; gap:9px; justify-content:flex-start;
  background:rgba(255,255,255,.07); color:#dbe6ff; border:1px solid rgba(255,255,255,.12);
  border-radius:9px; padding:9px 12px; font-size:13px; cursor:pointer; box-shadow:none; }
.theme-btn:hover { background:rgba(255,255,255,.14); transform:none; }
.sidebar .sb-note { font-size:10.5px; color:#6f82a6; padding:10px 4px 2px; }

/* main column + topbar */
.app-main { flex:1; min-width:0; display:flex; flex-direction:column; }
.topbar { position:sticky; top:0; z-index:10; display:flex; align-items:center;
  justify-content:space-between; gap:14px; padding:14px 26px;
  background:rgba(255,255,255,.82); backdrop-filter:blur(10px) saturate(1.4);
  border-bottom:1px solid var(--line); box-shadow:none; }
.topbar .tb-title h1 { margin:0; font-size:17px; font-weight:700; letter-spacing:-.01em; color:var(--ink); }
.topbar .tb-title p { margin:1px 0 0; font-size:12.5px; color:var(--mut);
  max-width:760px; white-space:nowrap; overflow:hidden; text-overflow:ellipsis; }
.app-main > .wrap { width:100%; }

@media (max-width:860px){
  .shell { flex-direction:column; }
  .sidebar { position:static; height:auto; width:100%; flex-direction:row; flex-wrap:wrap;
    align-items:center; gap:6px; padding:10px 12px; }
  .sidebar .brand { padding:4px 8px; } .sidebar .nv-grp { display:none; }
  .sidebar .nav { flex-direction:row; flex-wrap:wrap; gap:4px; }
  .sidebar .sb-foot { margin:0 0 0 auto; padding:0; } .sidebar .sb-note { display:none; }
  .theme-btn { width:auto; }
}

/* ============================================================================
   DARK MODE — CSS-variable overrides. Data-viz colors (blue/up/down/ok) unchanged.
   SVG panels with dark text are forced to a light surface so labels stay legible.
   ============================================================================ */
[data-theme="dark"] {
  --bg:#061214; --bg2:#0f2226; --card:#0e1e22; --ink:#e6f1ef; --ink2:#b6c9c6; --mut:#7d938f;
  --line:#1e3438; --line2:#16292c; --accent-soft:#0f2c2a; --gold-soft:#2a2210;
}
[data-theme="dark"] body {
  background:
    radial-gradient(1100px 520px at 100% -10%, #0a3330 0%, transparent 60%),
    radial-gradient(900px 520px at -10% 0%, #0a2c38 0%, transparent 55%),
    var(--bg);
}
[data-theme="dark"] body::before { opacity:.4; }
[data-theme="dark"] header { background:linear-gradient(115deg,#04191a 0%,#0a3a37 50%,#0d5f58 100%); }
[data-theme="dark"] .topbar { background:rgba(16,23,40,.82); border-bottom-color:#23304722; }
[data-theme="dark"] th { background:rgba(22,31,48,.94); color:var(--ink2); border-bottom-color:var(--line); }
[data-theme="dark"] th:hover { background:#1d2840; color:#c7d0fa; }
[data-theme="dark"] tbody tr:nth-child(even) td { background:#121a2b; }
[data-theme="dark"] tbody tr:hover td { background:#1b2742; }
[data-theme="dark"] code { background:#1c2840; color:#aab6ff; }
[data-theme="dark"] button.ghost { background:#16203a; color:var(--ink); border-color:var(--line); }
[data-theme="dark"] select, [data-theme="dark"] input { background:#0f1726; color:var(--ink); border-color:var(--line); }
[data-theme="dark"] .pill { background:#10301f; border-color:#1c5a37; }
/* keep SVG-chart panels (dark text inside) on a light surface even in dark mode */
[data-theme="dark"] #dvwrap, [data-theme="dark"] #upwrap, [data-theme="dark"] #scwrap,
[data-theme="dark"] .ev-card { background:#ffffff; }
[data-theme="dark"] a.tile, [data-theme="dark"] a.minor, [data-theme="dark"] a.mod,
[data-theme="dark"] .flow .step, [data-theme="dark"] .drug { background:var(--card); }

/* ============================================================================
   MOTION — scroll-reveal + count-up (app.js adds .in via IntersectionObserver). v4.
   ============================================================================ */
.reveal { opacity:0; transform:translateY(14px); transition:opacity var(--tr-slow), transform var(--tr-slow);
  transition-delay:var(--d,0ms); will-change:opacity,transform; }
.reveal.in { opacity:1; transform:none; }
@media (prefers-reduced-motion: reduce) {
  body::before { animation:none; }
  .reveal { opacity:1 !important; transform:none !important; transition:none; }
  * { scroll-behavior:auto !important; }
}

/* ============================================================================
   ELITE BADGES — Tier-1 driver / causally-supported / spatially-active. v4.
   ============================================================================ */
.badge { display:inline-flex; align-items:center; gap:5px; font-size:11px; font-weight:650;
  padding:3px 10px; border-radius:999px; background:var(--accent-soft); color:var(--accent-ink);
  border:1px solid transparent; letter-spacing:.01em; white-space:nowrap; }
.badge.elite { background:var(--gold-soft); color:var(--gold-ink); border-color:#f4d38a; }
.badge.mut { background:var(--bg2); color:var(--mut); }
.badge.up { background:#fdeceb; color:var(--up); } .badge.down { background:#e8f0f9; color:var(--down); }
[data-theme="dark"] .badge.up { background:#3a1614; } [data-theme="dark"] .badge.down { background:#12233a; }
[data-theme="dark"] .badge.elite { border-color:#5a4718; }

/* ============================================================================
   GENE TARGET PAGE (evidence.html) — the per-gene one-stop evidence dossier. v4.
   ============================================================================ */
.tgt-search { display:flex; gap:10px; align-items:center; flex-wrap:wrap; margin:4px 0 16px; }
.tgt-search input { flex:1; min-width:260px; font-size:15px; padding:12px 16px; border-radius:12px;
  box-shadow:var(--sh-sm); }
.tgt-hint { font-size:12.5px; color:var(--mut); }
.tgt-empty { text-align:center; color:var(--mut); padding:48px 16px; }
.tgt-empty .big { font-size:40px; margin-bottom:8px; opacity:.5; }
/* hero band */
.tgt-hero { display:flex; align-items:flex-start; gap:20px; flex-wrap:wrap; padding:20px 22px;
  border-radius:var(--r-lg); background:var(--card); border:1px solid var(--line); box-shadow:var(--sh);
  position:relative; overflow:hidden; }
.tgt-hero::before { content:""; position:absolute; left:0; top:0; bottom:0; width:4px;
  background:linear-gradient(180deg,var(--accent),var(--accent2)); }
.tgt-id { min-width:180px; }
.tgt-id .sym { font-size:30px; font-weight:800; letter-spacing:-.02em; line-height:1.05; }
.tgt-id .role { font-size:13px; color:var(--mut); margin-top:3px; }
.tgt-badges { display:flex; gap:7px; flex-wrap:wrap; margin-top:11px; }
.tgt-score { margin-left:auto; text-align:right; display:flex; gap:26px; flex-wrap:wrap; }
.tgt-score .sc { text-align:center; }
.tgt-score .sc .v { font-size:26px; font-weight:780; letter-spacing:-.02em;
  background:linear-gradient(120deg,var(--accent-ink),var(--accent2)); -webkit-background-clip:text;
  background-clip:text; -webkit-text-fill-color:transparent; }
.tgt-score .sc .k { font-size:10.5px; color:var(--mut); text-transform:uppercase; letter-spacing:.05em; }
/* evidence grid of cards */
.tgt-grid { display:grid; grid-template-columns:repeat(auto-fill,minmax(270px,1fr)); gap:14px; margin-top:16px; }
.tgt-sec { background:var(--card); border:1px solid var(--line); border-radius:var(--r-lg); padding:15px 17px;
  box-shadow:var(--sh-sm); transition:var(--tr); }
.tgt-sec:hover { box-shadow:var(--sh); border-color:#cfe0dd; transform:translateY(-2px); }
.tgt-sec.wide { grid-column:1/-1; }
.tgt-sec h3 { margin:0 0 10px; font-size:12px; font-weight:700; letter-spacing:.06em; text-transform:uppercase;
  color:var(--accent-ink); display:flex; align-items:center; gap:8px; }
.tgt-sec h3 .ic { font-size:15px; }
.tgt-row { display:flex; justify-content:space-between; align-items:baseline; gap:12px; padding:5px 0;
  border-bottom:1px dashed var(--line2); font-size:13px; }
.tgt-row:last-child { border-bottom:0; }
.tgt-row .k { color:var(--mut); } .tgt-row .v { font-weight:600; font-variant-numeric:tabular-nums; text-align:right; }
.tgt-row .v.na { color:var(--mut); font-weight:500; }
.tgt-sec .note { font-size:11.5px; color:var(--mut); margin-top:9px; line-height:1.5; }
/* mini bar for a 0-1 sub-score */
.tgt-bar { height:6px; border-radius:999px; background:var(--line2); overflow:hidden; margin-top:3px; min-width:64px; flex:1; }
.tgt-bar > i { display:block; height:100%; border-radius:999px;
  background:linear-gradient(90deg,var(--accent),var(--accent2)); }
.tgt-barrow { display:flex; align-items:center; gap:10px; padding:5px 0; font-size:12.5px; }
.tgt-barrow .k { color:var(--mut); min-width:104px; } .tgt-barrow .vn { width:34px; text-align:right; font-variant-numeric:tabular-nums; font-weight:600; }

/* topbar download button */
.tb-actions { display:flex; gap:8px; align-items:center; flex:0 0 auto; }
.dl-btn { display:inline-flex; align-items:center; gap:6px; font-size:13px; font-weight:550;
  padding:7px 13px; border-radius:8px; background:var(--card); color:var(--accent-ink);
  border:1px solid var(--line); box-shadow:var(--sh-sm); cursor:pointer; transition:var(--tr); }
.dl-btn:hover { background:var(--accent-soft); border-color:#d9d8fb; transform:translateY(-1px); box-shadow:var(--sh); }
[data-theme="dark"] .dl-btn { background:#16203a; color:#aab6ff; }